The Mammary Gland: A Tissue Sensitiveto Environmental Exposures
نویسندگان
چکیده
منابع مشابه
Environmental Exposures and Mammary Gland Development: State of the Science, Public Health Implications, and Research Recommendations
OBJECTIVES Perturbations in mammary gland (MG) development may increase risk for later adverse effects, including lactation impairment, gynecomastia (in males), and breast cancer. Animal studies indicate that exposure to hormonally active agents leads to this type of developmental effect and related later life susceptibilities. In this review we describe current science, public health issues, a...
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Kinetic properties and substrate specificity of the lysine transport system in porcine mammary gland were studied using mammary tissue explants from nine lactating sows. Sodium dependence of lysine uptake was determined by replacing sodium in the medium with choline. Kinetic parameters of lysine uptake were determined using lysine concentrations from 5 microM to 5.12 mM. Competition of lysine u...
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a lump in her left axilla which broke down discharging pus for a week. The discharge reappeared 10 days prior to admission to the hospital. Two days before her admission, she noticed a swelling on the left side of the left breast. On local examination, there was a sinus in the left axilla extending 3 inches deep from the skin, discharging a whitish thick fluid. Adjacent to the sinus, there was ...
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The udder is a very big organ weighing, around 50 kg (including milk and blood). However, weights up to 100 kg have been reported. Therefore, the udder has to be very well attached to the skeleton and muscles. The median ligaments are composed of elastic fibrous tissue, while the lateral ligaments are composed of connective tissue with less elasticity. If the ligaments weaken the udder will bec...
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BACKGROUND There are numerous examples of laboratory animals that were inadvertently exposed to endocrine disrupting chemicals (EDCs) during the process of conducting experiments. Controlling contaminations in the laboratory is challenging, especially when their source is unknown. Unfortunately, EDC contaminations can interfere with the interpretation of data during toxicological evaluations. W...
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ژورنال
عنوان ژورنال: Reviews on Environmental Health
سال: 2009
ISSN: 2191-0308,0048-7554
DOI: 10.1515/reveh.2009.24.4.319